Welcome everyone to Episode 102 of The Stem Cell Podcast. As always go to stemcellpodcast.com for all of our episodes and to sign up or re-subscribe (if you are a current subscriber) for the newsletter.
The Science Round Up
For this week’s round-up, STEMCELL Technologies would like to know what you think about the podcast. Please go to our website (stemcellpodcast.com) and click on the picture of the Starbucks mug to take our 2-min survey to let us know how we’re doing and what we can do to improve the show. You can also enter to win a $10 Starbucks card!
This week, in the world-famous Science Round Up, we discuss the latest science/stem cell news including:
- Body clock mechanism wins Nobel Prize.
- Mutation causal to pika brain defects?
- Bed bugs and dirty laundry.
- Senate and translational awards.
- Mini kidneys grown in the lab.
- Biobank of reversible mutant embryonic stem cells.
The interview with Sierra Marable
In the interview portion of this episode, STEMCELL Technologies introduces the Neural Stem Cells Wallchart. This wallchart provides an overview of how NSCs can be:
- Derived/cultured from various tissue sources,
- Differentiated into specific neuronal and glial subtypes,
- Also outlines opportunities for NSC-based therapies.
This wallchart was created in partnership with Nature Neuroscience and was co-authored by Clive Svendsen.
- Stem Cell Podcast listeners can get their free copies at https://www.stemcell.com/getNSCwallchart
- Hang it on your wall. Share it with your whole lab.
For the interview portion of the show of the show, The Stem Cell Podcast and STEMCELL Technologies welcome Sierra Marable, a graduate student in the Molecular and Developmental Biology Graduate Program at Cincinnati Children’s Hospital Medical Center. She previously worked at the Post-Baccalaureate Research Education Program (PREP) at the Wake Forest School of Medicine in North Carolina where she became interested in stem cell research while researching induced pluripotent stem cells as a method for modeling development and disease at the Institute for Regenerative Medicine. Sierra joins the show to talk to us about her research and life as a graduate student.
After the interview, we close the show with a signature SCP rant.
Resources, Links and Research Papers Mentioned in This Session Include:
Body Clock Mechanics Wins U.S. Trio the Nobel Prize in Physiology or Medicine – In this article, three Americans, Jeffrey C. Hall, Michael Rosbash, and Michael W. Young are recognized and won the Nobel Prize for discovering the cellular gears that drive circadian rhythms.
A Mutation May Explain the Sudden Rise in Birth Defects from Zika – According to this article, a single genetic mutation made the Zika virus far more dangerous by enhancing its ability to kill nerve cells in developing brains.
Bedbugs Are Attracted to Dirty Laundry – This article suggests that in the absence of humans to latch onto, bedbugs (Cimex lectularius) flock to dirty clothing.
About 1 In 5 Teens Has Had a Concussion – This article reports that about 20 percent of U.S. adolescents have had at least one concussion.
The HIV Triple-Threat – According to this article, combining the antibodies, called broadly neutralizing antibodies, may stop more strains of HIV than any single one can do alone.
Senate Panel Blocks NIH From Revising Translational Research Awards – This article reports that a congressional spending panel has backed scientists running a $516 million network of bench-to-bedside research centers in their fight with the National Institutes of Health (NIH) in Bethesda, Maryland, over how it manages the network.
Mini-Kidneys Grown in Lab Reveal Renal Disease Secrets – According to this article, by creating and manipulating mini-kidney organoids grown from human stem cells that contain a realistic micro-anatomy, UW Medicine researchers can now track the early stages of polycystic kidney disease.
A Biobank of Reversible Mutant Embryonic Stem Cells – In this article, scientists at IMBA developed a biobank of revertible, mutant embryonic stem cells.
A Labyrinth in a Chip – This article reveals a new chip with a labyrinth design that promises big improvements in detecting rare and aggressive cancer cells in the blood, helping doctors to anticipate tumor growth and plan customized treatments for their patients.
Photo Reference: Courtesy of Sierra Marable