Welcome to episode 106 of The Stem Cell Podcast. As always go to stemcellpodcast.com for all of our episodes and to sign up or re-subscribe (if you are a current subscriber) for the newsletter.
The Science Round Up
For this week’s round-up, STEMCELL Technologies would like to let listeners know about another one of their weekly science newsletters, Intestinal Cell News. This free, weekly newsletter curates all of the latest research, industry news, events, jobs and policy news impacting the field of intestinal cell biology. Subscribe to Intestinal Cell News to keep current with the field and save time at www.intestinalcellnews.com
This week, in the world-famous Science Round Up, we discuss the latest science/stem cell news including:
- How mosquitos interact with humans.
- Dolly the sheep’s arthritis is not from cloning.
- E-coli outbreak traced to raw flour.
- Current CRISPR gene drives too strong for outdoor use.
- Intestinal stem cells behavior may shed light on cancer.
- Drug-delivering nanoparticles seek and destroy cancer stem cells.
- How drinking affects neural stem cells.
- New stem cell treatment guidelines released by FDA.
The interview with Dr. Leigh Turner
In the interview portion of this episode, STEMCELL Technologies would like to introduce their one-stop resource for researchers who are using – or looking to use – organoids in their experiments. STEMCELL’s Organoid Information Hub provides scientists with instructional videos, educational webinars, expert interviews, technical tips and curated publications to help researchers set up and optimize organoids as a research model in their labs. Learn about organoid culture from the experts at STEMCELL. Visit www.stemcell.com/discover-organoids.
For the interview portion of the show of the show, The Stem Cell Podcast and STEMCELL Technologies are very pleased to welcome Dr. Leigh Turner. Dr. Turner is an associate professor in the center for Bioethics at the University of Minnesota. Turner’s research addresses ethical, legal, and regulatory issues associated with clinics engaged in direct-to-consumer marketing of unproven and unlicensed cell-based interventions. Dr. Turner is an author of numerous publications including a recent paper in Cell Stem Cell along with The Stem Cell Podcast’s past guest, Paul Knoepfler.
After the interview, we close the show with a signature SCP rant.
Resources, Links and Research Papers Mentioned in This Session Include:
New Insight on How Mosquitos Interact with Humans – This article reveals that nasty experiences can change an Aedes aegypti mosquito’s inclination to follow certain odors, such as the whiff of human skin.
Dolly the Sheep’s Severe Arthritis Not from Cloning – In this article, experts at the University of Nottingham and the University of Glasgow say original concerns that cloning caused early-onset osteoarthritis (OA) in Dolly the sheep are unfounded.
E. Coli Outbreak Traced to Raw Flour – This article reports that in 2015 and 2016, Escherichia coli-tainted flour sickened dozens of people in the United States, most of whom had eaten raw dough or batter while baking.
Current CRISPR Gene Drives Are Too Strong for Outdoor Use, Studies Warn – According to this article, a computer simulation released November 16 at bioRxiv.org predicts that standard forms of CRISPR gene drives, as the tools are called, can make tweaked DNA race through a population so easily that a small number of stray animals or plants could spread it to new territory.
Intestinal Stem Cells Behavior May Shed Light on Cancer – In this article, a team of researchers looked for signals and cellular responses of intestinal epithelial cells during growth and renewal.
Drug-Delivering Nanoparticles Seek and Destroy Elusive Cancer Stem Cells – This article reports that University of Illinois researchers are sending tiny drug-laden nanoparticles on a mission to seek and destroy cancer stem cells, the elusive and rare cells that can cause cancer to come back even when years have passed since the initial tumor was treated.
How Drinking Affects Neural Stem Cells – According to this article, new research suggests that long-term, heavy alcohol consumption kills off brain stem cells, which play a key role in supporting healthy cognitive function.
New Stem Cell Treatment Guidelines Released by FDA – In this article, U.S. Food and Drug Administration unveiled long-anticipated guidelines about stem-cell therapies that are meant to clear up confusion about which treatments are likely to be both appropriate and safe, and which pose the most risks and fewest rewards for patients.
Photo Reference: Courtesy of Dr. Leigh Turner