Alright everyone, we are so happy to be back after our short podcast break, and we are excited to kick things off with a fantastic guest. As always go to stemcellpodcast.com for all of our episodes and to sign up for the newsletter.
In this episode, our new hosts Dr.Kiki and Dr. Daylon James, introduce themselves and then move into the Science Round Up, sponsored by Biotechne and discuss the latest science/stem cell news including:
- Climate change effects on wine production,
- Males in US live shorter lives than from other countries,
- Drugs like Tylenol and Advil are bad for your heart,
- Restoring memories in Alzheimer’s patients,
- Making sperm from stem cells,
- A new CRISPR technique,
- A new reprogramming paradigm for blood stem cells,
- A core complex that regulates blood stem cell self-renewal.
For the interview portion of the show, sponsored by STEMCELL Technologies, we bring on stem cell researcher Dr. Joe Zhou from Harvard to discuss his work and latest paper in Cell Stem Cell. After this, our hosts rant about what to do with all the artwork kids bring home from school.
Below are all of the papers mentioned in this episode. Enter in your name and e-mail address below to have these paper summaries emailed to you directly when each episode is published.
Resources, Links and Research Papers Mentioned In This Session Include:
Climate Change to Affect Wine Quality – This article suggests that climate change has fundamentally altered the climatic drivers of early wine grape harvests in France, with possible ramifications for viticulture management and wine quality.
Men In US Have Lower Life Expectancies than Other Countries – This article presents the three main reasons why men in US have lower life expectancies which are: gun violence, drugs, and car accidents.
How To Tell If A T-Rex Is Pregnant – According to this article, scientists can determine if the Tyrannosaurus Rex is female and pregnant by the presence of medullary bone.
US Gets A Failing Grade on in Healthy Lifestyle Behavior – According to this article, only 2.7% of all adults had all 4 healthy lifestyle characteristics which are: being sufficiently active, eating a healthy diet, being a nonsmoker, and having a recommended body fat percentage.
Over The Counter Painkiller More Dangerous They You Think – This article describes the effects of taking non steroidal anti inflammatory drugs (NSAIDS) especially the risk of heart complications and bleeding.
Making Sperm from Stem Cells – In this article, researchers report complete in vitro meiosis from embryonic stem cell (ESC)-derived primordial germ cells (PGCLCs).
Four Key Genes Govern Growth, Multiplication Of Blood Stem Cells – This article shows cohesin as a major regulator of HSCs and illustrate the power of global RNAi screens to identify modifiers of cell fate.
Hematopoietic Reprogramming In Vitro Informs In Vivo Identification of Hemogenic Precursors to Definitive Hematopoietic Stem Cells – This article presents how reprogramming reveals a phenotype for in vivo precursors to hemogenic endothelium, establishing that direct in vitro conversion informs developmental processes in vivo.
A New CRISPR Advance – According to this article, CRISPRi system in iPSCs provides a powerful platform to perform genome-scale screens in a wide range of iPSC-derived cell types, dissect developmental pathways, and model disease.
Reprogrammed Stomach Tissue as a Renewable Source of Functional β Cells for Blood Glucose Regulation – In this article, scientists show that reprogramming of antral stomach cells assembled into bioengineered mini-organs in vitro yielded transplantable units that also suppressed hyperglycemia in diabetic mice, highlighting the potential for development of engineered stomach tissues as a renewable source of functional β cells for glycemic control.
Photo Reference: Courtesy of Dr. Joe Zhou