Welcome everyone to Episode 76 of The Stem Cell Podcast during which we talk to stem cell biologist Dr. Stephen Duncan on the topic of the purification of cell lineages derived from pluripotent stem cells. As always go to stemcellpodcast.com for all of our episodes and to sign up for the newsletter.
The Science Round Up
We begin with the world famous Science Round Up and discuss the latest science/stem cell news including:
- Nobel Prize winner discussion.
- Measles eliminated from the Americas.
- Facts about the “shady” sugar industry.
- Monsanto to use CRISPR.
- Scoring for antibodies.
- Gene mutation linked to Schizophrenia.
- Vitamin D increases number of blood stem cells.
The interview with Dr. Stephen Duncan
For the interview portion of the show, sponsored by STEMCELL Technologies, we bring on stem cell biologist Dr. Stephen Duncan from The Medical University of South Carolina to discuss his work on the purification of cell lineages derived from pluripotent stem cells. After the interview, we close the show with a signature SCP rant. Enjoy!
Below are all of the papers mentioned on the show. We are working on a way to categorize all of the research papers we mention and possibly even provide audio summaries. Enter in your name and e-mail address below, and we will notify you of when this feature is available.
Resources, Links and Research Papers Mentioned in This Session Include:
Japanese Scientist Receives Nobel Prize for Autophagy Work – In this article, Yoshinori Ohsumi, a biologist at the Tokyo Institute of Technology, won this year’s Nobel Prize in physiology or medicine for his work uncovering how cells break down old materials — a process critical for keeping cells healthy.
Measles Eliminated from The Americas – According to this article, the highly infectious disease – measles, which is marked by flat red spots that can cover the body, has been eliminated from the Americas after decades of wide-spread vaccination.
Uncovering Facts About the Shady Sugar Industry – In this article, researchers recently revealed that the sugar industry paid nutrition experts from Harvard University to downplay studies linking sugar and heart disease.
Gene Linked to Autism in People May Influence Dog Sociability – This article reveals that beagles with particular variants in a gene – SEZ6L – associated with autism were more likely to sidle up to and make physical contact with a human stranger.
Monsanto Buys Rights to CRISPR – According to this article, Monsanto is taking genetically engineered crops to the next level, buying a license from the Broad Institute of Harvard University and MIT to use the CRISPR/Cas9 gene-editing technology.
Dr. Allen Eaves of STEMCELL Technologies Inc. Named EY Entrepreneur of the Year™ Pacific 2016 – This article reports that Dr. Allen Eaves, Chairman, President and Chief Executive Officer of STEMCELL Technologies, a global biotechnology company that supplies tools and services to enable life science research, is this year’s Entrepreneur Of The Year Pacific winner.
Efficient Long-Term Cryopreservation of Pluripotent Stem Cells at −80 °C – In this article, researchers report that a medium comprised of Ficoll 70 and dimethyl sulfoxide (DMSO) in presence or absence of fetal bovine serum (FBS) can provide reliable cryopreservation of various kinds of human and porcine pluripotent stem cells at −80 °C for periods that extend up to at least one year, with the post-thaw viability, plating efficiency, and full retention of pluripotent phenotype comparable to that achieved with liquid nitrogen (LN2) storage.
Biologists Plan Scoring System for Antibodies – According to this article, biomedical experts plan to create a scoring system that will help researchers choose reliable antibodies for their experiments.
ULK4 Gene Mutation Linked To Schizophrenia – In this article, researchers have identified recently through genetic and in vitro functional studies, a novel serine/threonine kinase gene, unc-51-like kinase 4 (ULK4), as a rare risk factor for major mental disorders including schizophrenia.
Vitamin D Increases the Number of Blood Stem Cells During Embryonic Development – In this article, scientists hypothesize that the levels of vitamin D during fetal development may play a role in preventing the onset of blood-related disorders later in life.
Photo Reference: Courtesy of Dr. Stephen Duncan