Happy New Year everyone and welcome to Episode 82 of The Stem Cell Podcast. As always go to stemcellpodcast.com for all of our episodes and to sign up for the newsletter.
The Science Round Up
We begin with the world famous Science Round Up and discuss the latest science/stem cell news. Given this is the last episode recorded in 2016 we decided to recap some of the most exciting discoveries of the past year. This Science Round Up in this episode is brought to you by The Connexon Science Communications Newsletters. Here are some of the stories discussed:
- Zika is a worldwide public emergency.
- 10-year anniversary of IPS cell discovery.
- World’s first baby with 3 parents was born.
- Stem cells can make oocytes.
- CO2 turns into solid stone.
- In vivo gene editing improves muscle function.
- Arctic and Antarctic sea ice volumes drop to all time low.
- Humans are now getting CRISPR’d.
- Discovery of a new planet.
The interview with Dr. Daylon James
For the interview portion of the show, we talk to our very own Dr. Daylon James. In addition to hosting the Stem Cell Podcast, Daylon is an assistant professor at Weill Cornell Medical College in New York City where he uses stem cells as a tool to investigate cardiovascular and reproductive disorders.
Below are all of the papers mentioned on the show.
Resources, Links and Research Papers Mentioned in This Session Include:
World Health Organisation Declares a Public Emergency of International Concern Over Zika – This article reports that the World Health Organization declared the Zika virus and its suspected link to birth defects an international public health emergency, a rare move that signals the seriousness of the outbreak and gives countries new tools to fight it.
2016 Was 10 Year Anniversary of Yamanaka iPSC Paper – This article discusses the 10 years of iPSC where Cell published the original iPS cell papers, in which Dr. Kazutoshi Takahashi, Dr. Shinya Yamanaka and colleagues showed that mouse and human fibroblasts can be reprogrammed into pluripotent stem cells by introducing into them four genes.
World’s First Baby with Three Genetic Parents Was Born – According to this article, a five-month-old boy is the first baby to be born using a new technique that incorporates DNA from three people.
Stem Cells Can Make Oocytes – This paper reveals that scientists have for the first time reprogrammed murine embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs) into fully functional oocytes in the laboratory.
CO2 Turns into Solid Stone When Pumped into The Ground – In this article, researchers working in Iceland say they have discovered a new way to trap the greenhouse gas carbon dioxide (CO2) deep underground: by changing it into rock.
In Vivo Genome Editing Improves Muscle Function in A Mouse Model of Duchenne Muscular Dystrophy – According to this article, Exon 23 deletion by CRISPR/Cas9 resulted in expression of the modified dystrophin gene, partial recovery of functional dystrophin protein in skeletal myofibers and cardiac muscle, improvement of muscle biochemistry, and significant enhancement of muscle force.
Arctic and Antarctic Sea Ice Volumes Both Fall to an All-Time Low – This article reports that both the Arctic and Antarctic experienced record lows in sea ice extent in November, with scientists astonished to see Arctic ice actually retreating at a time when the region enters the cold darkness of winter.
Humans Are Now Getting CRISPR’d – This article reveals that a Chinese group has become the first to inject a person with cells that contain genes edited using the revolutionary CRISPR–Cas9 technique.
Proxima B – In this article, a newly discovered, roughly Earth-sized planet orbiting our nearest neighboring star might be habitable, according to a team of astronomers using the European Southern Observatory’s 3.6-meter telescope at La Silla, Chile, along with other telescopes around the world.
Major Stem Cell Discovery for Diabetes Retracted – According to this article, one of the highest-profile researchers in diabetes has retracted a paper once heralded as a breakthrough, following multiple failed attempts to reproduce its headline-grabbing results.
Gravitational Waves!!! – This article reports that the first gravitational wave signal detected by Laser Interferometer Gravitational-Wave Observatory (LIGO) came from the merger of two black holes spiraling inward, as depicted in this numerical simulation.
Photo Reference: Courtesy of Dr. Daylon James