Welcome everyone to Episode 83 of The Stem Cell Podcast. As always go to stemcellpodcast.com for all of our episodes and to sign up for the newsletter.
The Science Round Up
Last week we introduced the Connexon Newsletters as a new partner for the Science Roundup. Connexon has been publishing free, weekly newsletters that curate the latest research and news in various fields of cell biology for over 15 years. This week’s round-up is sponsored by Neural Cell News, which is sent to more than 5000 neuroscience researchers every week. Sign up at neuralcellnews.com to keep current with everything that is happening in the neural field.
We begin with the world famous Science Round Up and discuss the latest science/stem cell news including:
- Cancer death rates fall.
- Ebola vaccine proves successful.
- Announcement of a new stem cell resource.
- A new protocol for liver progenitor cells.
- Synthetic stem cells for heart regeneration.
- Stem cells to grow stomachs.
The interview with Dr. Hongjun Song
In this episode, we bring on Dr. Hongjun Song, Director of the Stem Cell Program at John Hopkins University. The research in the Song laboratory focuses on understanding mechanisms regulating neural stem cells and neurogenesis in the mammalian brain. Using neural stem cells as tools, the team explores molecular mechanisms underlying mental disorders with the goal of developing novel strategies for treatment of degenerative neurological disorders. He recently published a review regarding Zika virus, what’s known, how stem cells can help and we talk with him about this topic and more. After this we close the show with a signature SCP rant.
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Resources, Links and Research Papers Mentioned in This Session Include:
Cancer Death Rates Fall as Prevention, Treatment Advance – According to this article, deaths from cancer in the United States have dropped 25 percent since hitting a peak in 1991 attributed to reductions in smoking and advances in early detection and treatment.
Ebola Vaccine Proves Effective, Final Trial Results Show – This article reports that of 5,837 people in Guinea who received a single shot of the vaccine, rVSV-ZEBOV, in the shoulder, none became infected with the Ebola virus 10 to 84 days after vaccination.
Among High School Seniors, Interest in Science Varies by Race, Ethnicity – In this article, a majority of high school seniors in the U.S. say they enjoy science and around four-in-ten (44%) would like to have a job in the field although this tend to vary by race and ethnicity – a pattern that also is reflected in American students’ test scores in science.
Figuring Out How Women Respond to Hormones – In this article, researchers suppressed then added back the hormones estrogen and progesterone in women with premenstrual dysphoric disorder (PMDD) and found that their symptoms disappear only to re-emerge when the hormones were added back.
NYSCF and PGP Announce Availability of Unique New Stem Cell Resource for Scientific Research – This article reports that the New York Stem Cell Foundation (NYSCF) Research Institute and the Personal Genomes Project (PGP) announced the availability of a unique new stem cell resource – the stem cell lines – for scientists around the world.
Conversion of Terminally Committed Hepatocytes to Culturable Bipotent Progenitor Cells with Regenerative Capacity – According to this article, researchers report that a cocktail of small molecules, Y-27632, A-83-01, and CHIR99021, can convert rat and mouse mature hepatocytes (MHs) in vitro into proliferative bipotent cells, which they called chemically induced liver progenitors (CLiPs).
Synthetic Stem Cells to Regenerate Heart Tissue – This article reveals that American and Chinese researchers have developed synthetic cardiac stem cells that could have the same therapeutic impact as human stem cells, with the added benefit of reducing the risk of graft rejection in cellular therapy.
Using Stem Cells to Grow Stomachs? – According to this article, a study featured in the journal Nature reveals that researchers from the Cincinnati Children’s Hospital Medical Center were able to grow human tissues in a laboratory using stem cell samples taken from the corpus/fundus region of the stomach.
Photo Reference: Courtesy of Dr. Hongjun Song