Welcome everyone to Episode 85 of The Stem Cell Podcast. As always go to stemcellpodcast.com for all of our episodes and to sign up for the newsletter.
The Science Round Up
This week’s round-up is sponsored by Cell Therapy News (CTN), the original Connexon newsletter. Launched in 2002, Cell Therapy News has been covering the world of stem cell therapy, regenerative medicine and gene therapy for 15 years. Go to CellTherapyNews.com to sign up for free to save time and keep current on the latest research and news.
We begin with the world-famous Science Round Up and discuss the latest science/stem cell news including:
- Scientists plan to march.
- CRISPR in cows.
- Using an artist’s amnesia to investigate memory.
- Human-Pig chimera.
- Brain cancer stem cells avoid immune system.
- Generating thyroid cells from stem cells.
- Generating Leydig-like cells via direct reprogramming.
The interview with Dr. Christopher Park
Today’s interview segment is brought to you by STEMCELL Technologies. Culture your expertise in hematopoiesis with their new webinars, tech tips and expert interviews. Listeners may be interested in the recent webinar with Dr. Suzan Imren where she discusses her work regarding the roles of notch and small molecule UM171 on the in vitro expansion of cord blood HSCs in vitro. Start exploring now at stemcell.com/HemaHub
For the interview portion of the show, sponsored by STEMCELL Technologies, we bring on Dr. Christopher Park, Associate Professor and Director of Pathology Education and Translational Research at the NYU Langone Medical center. His lab is currently looking at new ways to combat blood cancers like Leukemia by attacking and destroying the blood stem cells. In this episode, Dr. Park discusses his lab’s work and the details of their most recent publication in Science Translational Medicine. After this we close the show with a signature SCP rant.
Resources, Links and Research Papers Mentioned in This Session Include:
Scientists Plan to March – This article reports that a few months from now, thousands of scientists will leave their labs and take to the streets to rally on behalf of publicly funded, openly communicated, evidence-based research.
CRISPR Used in Cows to Help Fight Tuberculosis – In this article, researchers are able to obtain transgenic cattle with increased resistance to tuberculosis through somatic cell nuclear transfer.
An Artist’s Amnesia Could Help Better Understand Memory – According to this article, despite having amnesia, artist Lonni Sue Johnson can still create art, which makes neuroscientists curious about Johnson’s brain in part because her education and expertise before her illness contrast sharply with that of the most famous amnesiac known to science, Henry Molaison.
Shining Light on Eggs Leads to More “Chilled” Out Chickens – In this article, researchers at the University of California –Davis found that broilers given at least 12 hours of light daily during incubation were less fearful.
First Human-Pig ‘Chimera’ Created in Milestone Study – In this article, scientists from the Salk Institute have created a human-pig hybrid in a milestone study that raises the prospect of being able to grow human organs inside animals for use in transplants.
Study by Cleveland Clinic Researchers Explains How Brain Cancer Cells Avoid Immune System – According to this article, a new study by Cleveland Clinic researchers has uncovered some of the mystery behind what enables glioblastoma – one of the most deadly and recurring brain cancers – to resist most cancer treatments, including chemotherapy, radiation and immunotherapy.
Endocrinology Stem Cell Research Engineering Thyroid Cells from Stem Cells May Lead to New Therapies – In this article, researchers found a way to coax genetically modified embryonic stem cells from mice to develop into thyroid cells.
Direct Reprogramming of Mouse Fibroblasts toward Leydig-like Cells by Defined Factors – This article reveals that the induced Leydig-like cells (iLCs) expressed steroidogenic genes, had a global gene expression profile similar to that of adult LCs, and acquired androgen synthesis capabilities.
Photo Reference: Courtesy of Dr. Christopher Park