Welcome everyone to Episode 93 of The Stem Cell Podcast. As always go to stemcellpodcast.com for all of our episodes and to sign up or re-subscribe (if you are a current subscriber) for the newsletter.
The Science Round Up
For this week’s round-up, STEMCELL Technologies would like to remind everyone about one of Connexon’s most popular newsletters, Neural Cell News. As with all 20 of Connexon’s science newsletters, Neural Cell News is sent weekly to your inbox for free. It summarizes the latest research, industry news, policy, events and jobs in the neuroscience field. Specific research topics include neural development and neuroregeneration, neural signaling related to cellular responses and behavior, and synaptic plasticity. Research into the diagnosis, progression, cellular characteristics and treatment of brain diseases such as Parkinson’s, MS, Alzheimer’s, ALS and various brain cancers, as well as brain damage is also covered. Subscribe at neuralcellnews.com.
This week, in the world-famous Science Round Up, we discuss the latest science/stem cell news including:
- New administration set to bludgeon science budget.
- Mouse sperm survive on spaceship.
- 40 more intelligence genes identified.
- Statin drugs may not benefit adults.
- Bookmarks on stem cells?
- Emphysema and stem cells.
- A stem cell baldness cure?
The interview with Dr. Clive Svendsen
Before we jump into the interview portion of this episode, STEMCELL Technologies has a new product line called iCell® from Cellular Dynamics International (CDI).
- iCell® human iPSC-derived products exhibit functional characteristics similar to those of native human cell types and can be used as physiologically relevant models in a variety of applications including drug discovery, toxicity testing and regenerative medicine research.
- iCell® differentiated iPSCs are derived from a single iPSC line and large batch sizes ensure consistency across multiple experiments.
- The iCell® product line includes DopaNeurons and GlutaNeurons among other cell types
DopaNeurons and GlutaNeurons are highly pure, fully differentiated populations of dopaminergic and glutamatergic neurons respectively.
- To learn more, please visit stemcell.com/dopaneuronsor www.stemcell.com/glutaneurons.
For this episode’s interview, The Stem Cell Podcast and STEMCELL Technologies welcome Dr. Clive Svendsen. Dr. Svendsen is the Director of the Board of Governors Regenerative Medicine Institute and Professor of Biomedical Sciences at Cedar Sinai Medical Center.
Dr. Svendsen’s lab uses stem cells to investigate neural disease. One focus of his current research is to derive cells from patients with specific disorders which can then be “reprogrammed” to a primitive state and used as powerful models of human disease. The other side of his research involves cutting edge clinical trials. We were thrilled to have Dr. Svendsen join us and discuss his work and most recent publication.
After the interview, we close the show with a signature SCP rant.
Resources, Links and Research Papers Mentioned in This Session Include:
New Administration Budget Would Bludgeon Science Funding – According to this article, under President Donald Trump’s 2018 budget proposal, federal research spending would decline abruptly.
Mouse Sperm Survive Trip to Space – This article reports that sperm freeze-dried and sent into space for months of exposure to high levels of solar radiation later produced healthy baby mice.
40 More Intelligence Genes Identified – According to this article, by sifting through the genetics of nearly 80,000 people, researchers have uncovered 40 genes that may make certain people smarter which brings the total number of suspected “intelligence genes” to 52.
Statin Drugs May Not Benefit Older Adults – This article reveals that statins did not cause a meaningful reduction in heart attacks, coronary heart disease deaths or deaths from any cause in people age 65 and older.
Bookmarks on Stem Cells – This article shows that stem cells preserve their identities after cell division by using a series of protein “bookmarks” on their genes, according to new research published by scientists at Weill Cornell Medicine.
High-Throughput Protocol for Deriving Microglia from Human Stem Cells – In this article, scientists from the New York Stem Cell Foundation (NYSCF) Research Institute have developed a robust, efficient method for deriving microglia, the immune cells of the brain, from human stem cells according to a paper published in Stem Cell Reports.
HIV May Cause Emphysema by Taking Over Stem Cells – In this article, HIV may cause emphysema by reprogramming the stem cells, called basal cells, to produce enzymes that can destroy lung tissue.
A Cure for Baldness? – According to this article, scientists have found that immune system cells that control inflammation play a key role in hair growth.
Photo Reference: Courtesy of Dr. Clive Svendsen