Welcome everyone to Episode 97 of The Stem Cell Podcast. As always go to stemcellpodcast.com for all of our episodes and to sign up or re-subscribe (if you are a current subscriber) for the newsletter.
The Science Round Up
For this week’s round-up, STEMCELL Technologies would like to introduce Cord Blood News, a newsletter that we haven’t mentioned on the podcast yet. Sent to almost 5000 researchers globally, Cord Blood News has been summarizing the field of cord blood stem cell research for 8 years. Subscribe for free at www.cordbloodresearchnews.com
This week, in the world-famous Science Round Up, we discuss the latest science/stem cell news including:
- Cows produce HIV antibodies.
- Rising temps = less commercial flights?
- CRISPR to store movies in DNA.
- One night of bad sleep can increase Alzheimer’s proteins.
- New approach to kill brain tumor cells.
- Schizophrenia induced mice by injecting iPSC derived cells.
- Arteries from stem cells.
The interview with Dr. Mark Tomishima
For the interview portion of the show, The Stem Cell Podcast and STEMCELL Technologies welcome Dr. Mark Tomishima. Mark is an Associate Laboratory Member and Sloan Kettering Institute Stem Cell Research Facility Manager. Mark joins us to talk about all things stem cells, including his latest published work on standardizing protocols that start with Pluripotent Stem Cells.
The interview portion of this episode is brought to you STEMCELL Technologies. STEMCELL Technologies provides a cutting-edge cryopreservation reagent called FreSR-S™
- Traditionally, human pluripotent stem cells are frozen as clumps to facilitate their recovery post-thaw.
- Unlike conventional methods, FreSR-S™ has been designed to cryopreserve pluripotent stem cells in single-cell suspensions.
- With recovery efficiency and viability rates of up to 80%, FreSR-S™ greatly improves the complete cryopreservation process.
- Furthermore, stable karyotypes have been consistently reported after multiple freeze-thaw cycles.
- For more information about efficiently cryopreserving pluripotent stem cells, please visit stemcell.com/fresr-s
After the interview, we close the show with a signature SCP rant.
Resources, Links and Research Papers Mentioned in This Session Include:
Cows to Produce HIV Antibodies – This article reveals that in a first for any animal, including humans, four cows injected with a type of HIV protein rapidly produced powerful antibodies against the virus.
Rising Temps = Less Commercial Flights – According to this article, steadily rising mean and extreme temperatures as a result of climate change will likely impact the air transportation system over the coming decades.
CRISPR To Store Movies In DNA – In this article, a team from Harvard University use the current trendy gene-editing system CRISPR to encode images and a short movie into the DNA of living bacteria.
Drinking Sugary Beverages in Pregnancy Linked to Kids’ Later Weight Gain – According to this article, the more sugary beverages a mom drank during mid-pregnancy, the heavier her kids were in elementary school compared with kids whose mothers consumed less of the drinks.
Just One Night of Poor Sleep Can Boost Alzheimer’s Proteins – This article reports that sleep deprivation increases amyloid-β, suggesting that chronically disrupted sleep may promote amyloid plaques and other downstream Alzheimer’s disease pathologies including tauopathy or inflammation.
Innate Reaction of Hematopoietic Stem Cells to Severe Infections – In this article, researchers have shown that hematopoietic stem cells detect infectious agents themselves and begin to divide – that is, without signals from growth factors.
New Approach to Kill Tumor Cells in The Brain – According to this article, a team of investigators from Brigham and Women’s Hospital and the Harvard Stem Cell Institute has developed cancer-killing viruses that can deliver stem cells via the carotid artery, and applied them to metastatic tumors in the brains of clinically relevant mouse models.
Human Cells from Schizophrenia Patients Injected into Newborn Mice Render Them Schizophrenic Like – In this article, lab mice whose brains were injected with cells from schizophrenia patients became afraid of strangers, slept fitfully, felt intense anxiety, struggled to remember new things, and showed other signs of the mental disorder.
Bioengineered Arteries Grown from Stem Cells – This article reports that scientists for the first time have produced cells that grow into fully functional arteries and they are on their way to clinical applications.
Photo Reference: Courtesy of Dr. Mark Tomishima