Welcome everyone to Episode 90 of The Stem Cell Podcast. As always go to stemcellpodcast.com for all of our episodes and to sign up or re-subscribe (if you are a current subscriber) for the newsletter.
The Science Round Up
For this week’s round-up, we have another Connexon Newsletter to introduce this week: Extracellular Matrix News! ECM News is sent out for free, every week, to researchers around the world who are interested in ECM biology. Keep current with the latest research, news, events and jobs related to the ECM at http://www.extracellularmatrixnews.com
This week, in the world-famous Science Round Up, we discuss the latest science/stem cell news including:
- Budget cuts can increase “sloppy” science.
- Device to pull water from air.
- CRISPR used to detect viruses.
- 3D cell library.
- The EPS cell, a new stem cell.
- Transcriptional variability amongst iPSC lines.
- In vivo reprogramming for Parkinson’s disease.
- iPSC derived endothelial cells to investigate hypertension.
The interview with Dr. Alysson Muotri
In the interview portion of this episode, STEMCELL Technologies announces a new product called CloneR™. Here are the highlights:
- Editing the pluripotent stem cell genome relies heavily on the survival of single cells to establish clonal cell lines.
- CloneR™ is a medium supplement designed for greatly enhancing the cloning efficiency and single-cell survival of pluripotent stem cells.
- Unlike current methods, CloneR™ will enable the robust generation of clonal cell lines without single-cell adaptation, thus minimizing the risk of acquiring genetic abnormalities.
- CloneR™ is coming soon!
Stem Cell Podcast listeners can sign up to receive notification when this product becomes available. Go to www.stemcell.com/cloner to sign up.
For this episode’s interview, we bring on Dr. Alysson Muotri, a Professor at the School of Medicine, University of California in San Diego. Dr. Muotri’s research focuses on modeling neurological diseases, such as Autism Spectrum Disorders, using human induced pluripotent stem cells. His lab has developed several techniques to culture human neurons and glia for basic research and drug-screening platforms. Most recently he and his group published a paper reporting the first cellular model of anorexia nervosa (AN), reprogramming induced pluripotent stem cells (iPSCs) derived from adolescent females with the eating disorder. After this conversation, we close the show with a signature SCP rant.[Read more…]