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Next Generation Scientists – Trainee Feature

September 7, 2021

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Bria Macklin, Matthew Sinton, Leili Rohani

Bria Macklin, Matthew Sinton, Leili Rohani

Dr. Bria Macklin is a Postdoctoral Fellow at the Gladstone Institutes. Her PhD research at Johns Hopkins used functional assays to characterize the interactions between different vascular cell types in 3D, how they respond to low-oxygen environments, and whether they have therapeutic capability in a diabetic retinopathy mouse model. Her current lab uses stem cell differentiation and morphogenesis to engineer three-dimensional, multicellular systems.

Dr. Matthew Sinton is a Postdoctoral Research Assistant at the University of Glasgow. In his PhD, Dr. Sinton developed a new human pluripotent stem cell model of non-alcoholic fatty liver disease, and used it to explore the effects of hepatic lipid accumulation on mitochondrial energy metabolism. His current postdoctoral project centers around TH2 immunity, and how it is regulated by infection-associated metabolic changes.

Dr. Leili Rohani is a Scientist at the Centre for Heart Lung Innovation at the University of British Columbia. Her current research involves digging into human heart cells at a molecular level to determine how diseased cells regulate gene expression, which cells are disrupted in disease progression, and how potential therapies would impact their function.

Listen to the episode here.


September 7