Dr. Margaret Goodell is Professor and Chair of Molecular and Cellular Biology, Vivian L. Smith Chair in Regenerative Medicine, and
Director of the Stem Cell and Regenerative Medicine Center at Baylor College of Medicine.

The Goodell lab studies HSCs as a paradigm to understand the general mechanisms governing adult stem cells, and how dysregulation of some of these pathways leads to malignancy development. They use a combination of approaches including biochemistry, generation of novel mouse models, and examination of human samples, to study how the DNMT3A mutation promotes malignancy development.