Welcome everyone to Episode 88 of The Stem Cell Podcast. On this episode, we speak with Dr. Shawn Hingtgen on the topic of “Homing Neural Stem Cells.”
The Science Round Up
This week’s science round-up is sponsored by Neural Cell News, which is sent to more than 5000 neuroscience researchers every week. Sign up at neuralcellnews.com to keep current with everything that is happening in the neural field.
This week, in the world-famous Science Round Up, we discuss the latest science/stem cell news including:
- The new, anti-science agenda.
- Making mistakes makes your brain pause.
- Genetically engineered corn to ward off fungus.
- 3 women blinded by unproven stem cell treatment.
- How the body controls stem cells.
- Turning old gut stem cells young.
- New antibody therapy that targets cancer stem cells.
The interview with Dr. Shawn Hingtgen
The interview portion of this episode is sponsored by STEMCELL Technologies, who is offering a free sample of a NeuroCult NS-A for Brain Tumor Stem Cells. It’s the most referenced specialized culture medium for brain tumor stem cell culture which:
- Supports the isolation and proliferation of brain tumor stem cells from both pediatric and adult tumors, and from a variety of CNS tumor types
- Gives you an advantage because it’s:
- Specialized – maintain humans neural/brain tumor stem cells in long-term culture
- Versatile – supports a variety of tumor types, using either neurosphere or monolayer culture techniques
- Consistent – Conforms to stringent quality control standards
The Stem Cell Podcast listeners can request a free sample at www.stemcell.com/SampleNeuroCult.
For this episode’s interview, we bring on Dr. Shawn Hingtgen, Assistant Professor Department of Molecular Pharmaceutics at UNC Eshelman School of Pharmacy, and Dr. Matthew G. Ewend, Chair of the Department of Neurosurgery at UNC School of Medicine. Dr. Hingtgen’s research focuses on utilizing molecular imaging to characterize and validate novel stem cell-based targeted therapeutics for treatment of highly aggressive brain cancers. Most recently, Hingtgen and Ewend published a paper in Science Translational medicine describing a novel method using neural stem cells to home to and infiltrate brain tumors in mouse models. After this we close the show with a signature SCP rant.
Resources, Links and Research Papers Mentioned in This Session Include:
New Administration Will Deeply Cut Science Budgets – According to this article, the harshest budget cuts appear to be directed at biomedical research, which will see a dramatic 20 percent drop in funding for the National Institutes of Health
Making A Mistake Can Make Your Brain Pause – This article reveals that when facing a fast and furious stream of decisions, even the momentary distraction of noting an error can decrease accuracy on the next choice.
Genetically Engineered Corn to Ward Off Fungal Growth – In this article, genetically altered corn infected with Aspergillus fungus may be able to prevent the fungus from releasing carcinogenic toxins or aflatoxins.
Insight into Neandertals’ Diet and Disease from Preserved Dental Plaque – According to this article, dental plaque preserved in fossilized teeth confirms that Neandertals were flexible eaters and may have self-medicated with an ancient equivalent of aspirin.
3 Women Blinded by Unproven Stem Cell Treatments – This article reports that researchers document the cases of three elderly women who were blinded after getting stem cells derived from fat tissue at a for-profit clinic in Florida.
A New Report Aims to Decipher How the Body Controls Stem Cells – In this article, researchers from the Luxembourg Centre for Systems Biomedicine (LCSB) of the University of Luxembourg and an international team have now identified an ingenious mechanism by which the body orchestrates the regeneration of red and white blood cells from progenitor cells.
A New Antibody Therapy That Targets Cancer Stem Cells – In this article, scientists have described a novel antibody therapy with a two-in-one antibody, called CT16, that may be able to both shrink tumors and target CSCs.
Photo Reference: Courtesy of Dr. Shawn Hingtgen