Ep 142: “Beta-Cell Proliferation and Diabetes” Featuring Dr. Adrian Teo
Dr. Adrian Teo is a Principal Investigator at the Institute of Molecular and Cell Biology at the Agency for Science, Technology and Research (A*STAR) in Singapore. His research focuses on using stem cell technology to model human pancreatic development in vivo and to study the mechanisms that cause diabetes and underlie diabetic complications.
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Resources and Links
Advancing Cell Therapies for Diabetes – Researchers mapped stem cell-derived beta cell differentiation, and developed an improved process for purifying beta cells, which can be used to enhance cell therapies for diabetes.
Essential Role of YAP in Liver Regeneration – YAP signaling, which activates the transcription of certain genes, has been shown to be necessary for the survival and regeneration of liver epithelial cells upon injury.
Gene Therapy Repairs Heart Attack Damage in Pigs – Expression of a microRNA delivered by adeno-associated viral vectors stimulated cardiac repair in pig hearts following a heart attack.
How Low Oxygen Affects the Premature Brain – Using 3D brain-region-specific organoids, research have identified certain brain cells that are susceptible to harm from exposure to oxygen deprivation during early development.
Tumor-Initiating Cells Addicted to Methionine – Scientists have found that tumor-initiating cells are metabolically dependent on methionine, providing a potential therapeutic target.
Photo Reference: Courtesy of Dr. Adrian Teo