Guest:

Dr. Todd McDevitt is a Senior Investigator at the Gladstone Institutes. He is also Program Director of the University of California, San Francisco’s Bioengineering Graduate Program (joint with UC Berkeley), and a Professor at UCSF’s Department of Bioengineering and Therapeutic Sciences. His research focuses on engineering 3D, multicellular systems that can be used to study principles of stem cell and developmental biology.

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The Stem Cell Science Round Up

Improving Stem Cell Therapy for Spinal Cord Injury – Researchers have found that modulating the microenvironment of neurons after a spinal cord injury can improve the efficacy of neural progenitor cell grafts.

Brain Organoids Reveal Glioblastoma Origins – Scientists have created a glioblastoma tumor cell atlas that demonstrates heterogeneity, and used cortical organoids to model tumor invasion.

Single-Cell Profiling of the Human Heart – Investigators analyzed cells from normal, failed, and partially recovered human hearts at single cell resolution to better understand the cellular composition and interactions of the adult human heart.

Engineering Chamber-Specific Heart Models – Clinically relevant engineered heart tissues were generated from hPSCs, and were successful in modeling cardiac disease.

Photo Reference: Courtesy of Dr. Todd McDevitt