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Guest:
Dr. Thomas Reh is a Professor of Biological Structure at the University of Washington School of Medicine. His lab is studying retinal development and disease using organoids, and developing methods of transplanting stem cells for retinal repair in non-human primates. Their goal is to stimulate more effective regeneration in the retina to restore vision in people that have lost their sight.
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The Stem Cell Science Round Up
Curing Cystic Fibrosis in Human Cells – Investigators have safely edited and repaired mutations in the CFTR gene using a Cas9 alternative in human cells derived from a cystic fibrosis intestinal organoid biobank.
New Technique to Analyze Cancer Organoids – A new mass spectrometry technique has enabled the analysis of post-translational modifications and cell-type-specific signaling in intestinal organoids.
Scientists Discover How the Intestine Heals Itself – Researchers have found that restoration of damaged intestinal stem cells is due to de-differentiation of their daughter cells, rather than through a reserve pool of stem cells.
Improved Stem Cell Model of Early Developing Mouse Embryo – Scientists have developed a more advanced method for generating gastruloids – complex embryo-like structures developed from mouse embryonic stem cells.
Photo Reference: Courtesy of Dr. Thomas Reh
