Guest:

Dr. Joy Wu is an Associate Professor of Medicine at Stanford University, and a a board-certified endocrinologist.  With both basic and translational research, her lab investigates stem cell therapies for bone formation and the prevention of cancer metastases to bone, as well as the bone marrow hematopoietic niche.

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The Stem Cell Science Round Up

Diabetes in Mice Cured with Stem Cells – By targeting the cytoskeleton, investigators were able to improve the differentiation of pluripotent stem cells to pancreatic β cells, and reverse diabetes when transplanting the cells into mice.

New CRISPR Tools for Knock-Ins – A new CRISPR tool, called CRISPR–HOT, enables fast and efficient generation of knock-in human organoids through non-homologous end joining.

Making Humanized Organs in Pigs – Host endothelium in donor organs is a source of immune rejection. Researchers generated viable human-pig chimeric embryos whose endothelial cells were entirely human-derived.

Scorpion Toxin to Target Brain Cancer – A clinical trial has been launched to evaluate a CAR T-cell therapy for glioblastoma that uses a scorpion venom peptide.

Photo Reference: Courtesy of Dr. Joy Wu