Guest:

Dr. Stephen Sullivan is the Program Manager and International Liaison Officer at the Global Alliance for iPSC Therapies (GAiT), an international initiative to support the implementation and clinical application of therapies derived from pluripotent stem cells to the benefit of patients globally. GAiT serves as a central, international resource for those organisations who are developing therapies from clinical-grade induced pluripotent stem cells and to support the expansion of this nascent field.

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The Stem Cell Science Round Up

Stem Cells in Wound Healing – Scientists found that Lgr6 epidermal stem cells interact with nerves and specialize in wound resurfacing.

A ‘Telescope’ Model for Hair Follicle Development  – Researchers used long-term live imaging and single-cell transcriptomics to study the development of mouse whisker hair follicles.

Base Editing Rescues Sickle Cell Disease – Scientists used base editing to correct the mutation that causes Sickle Cell Disease in HSPCs from patients.

Age-Related Genetic Changes in HIV – Researchers found people with HIV had higher rates of clonal hematopoiesis, a condition caused by mutations in HSCs that may be associated with inflammation and contributes to comorbidities.

Photo Reference: Courtesy of Dr. Stephen Sullivan