Ep. 222: “Protein Delivery Vehicles for Regenerative Medicine” Featuring Dr. Marian Hettiaratchi
Dr. Marian Hettiaratchi is an Assistant Professor at the Knight Campus at the University of Oregon. Her research focuses on affinity-based biomaterials to promote tissue and bone repair. She talks about the delivery vehicles for these biomaterials, and her recent work on heparin-mediated delivery of BMP-2 to promote bone regeneration.
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The Stem Cell Science Round Up
DNA Replication Errors in Preimplantation Embryos – DNA replication stress in human preimplantation embryos predisposes gene-poor regions to fragility and to the formation of aneuploidies, impairing developmental potential.
Stem Cell Movement in the Intestine – The number of effective stem cells in small intestinal crypts is determined by Wnt-dependent retrograde cellular movement.
Inflammation Affects HSC Self-Renewal – Inflammation and infection irreversibly depletes functional HSCs.
Colon Cancer Stem Cell Dormancy – Researchers used a lineage-tracing system to identify LGR5+ cancer stem cells that drive cancer growth after chemotherapy.
Photo Reference: Courtesy of Dr. Marian Hettiaratchi