Ep. 229: “Cellular Reprogramming and Pluripotency” Featuring Dr. Jacob Hanna
Dr. Jacob Hanna is an Associate Professor at the Weizmann Institute of Science. His lab investigates cellular reprogramming and embryogenesis. He talks about the challenges of growing synthetic embryo models in a roller culture system and the feasibility of making human gametes. He also discusses his startup, Renewal Bio, the ethical discussions surrounding stem cell-derived embryos, and creating a more inclusive and equitable scientific community.
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The Stem Cell Science Round Up
Oocytes Store mRNAs around Mitochondria – Researchers discovered that mammalian oocytes store maternal mRNAs around the mitochondria in a membraneless compartment with hydrogel-like properties.
Skeletal Stem/Progenitor Cells in Bone Injury Repair – Different cell types are primarily responsible for repairing different types of bone injuries.
How Glioblastoma Stem Cells Drive Cancer Progression – Glioblastoma stem cell-secreted histamine promotes glioblastoma progression by increasing angiogenesis.
Organogenesis in a Dish – Scientists engineered vascularized, perfusable human enteroids to model innate immune responses in inflammatory bowel disease.
Photo Reference: Courtesy of Dr. Jacob Hanna