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Ep. 241: “The Biology of HSCs” Featuring Dr. Shannon McKinney-Freeman

Shannon McKinney-Freeman


Dr. Shannon McKinney-Freeman is a Principal Investigator and Member at St. Jude Children’s Research Hospital. Her lab focuses on the fundamental biology of hematopoietic stem cells (HSCs).  She talks about the role of HSCs in sickle cell disease and the state of HSC transplantation research. She also discusses her work on hematopoietic progenitor expansion.

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The Stem Cell Science Round Up

De-Differentiation to Prevent Grey Hair – Scientists identified a new model whereby dedifferentiation is integral to homeostatic stem cell maintenance.

Seeing Stem Cell Variants – Researchers used single-cell cloning technologies to generate libraries of basal stem cells from idiopathic pulmonary fibrosis and control lungs.

How Exercise Rejuvenates Stem Cells – Exercise increases Osteopontin expression in muscle and improves muscle regeneration.

Distal Memory in Wound Healing – Cell adaptation resulting from localized tissue damage has a wide spatial impact.

Photo Reference: Courtesy of Dr. Shannon McKinney-Freeman

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