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Ep. 247: “Neurological Disorders” Featuring Dr. Thomas Durcan

By July 25, 2023No Comments

Thomas Durcan


Dr. Thomas Durcan is an Associate Professor and Director of the Early Drug Discovery Unit at the Montreal Neurological Institute. He oversees a team of 40+ research staff and students, committed to applying patient-derived stem cells towards the development of phenotypic discovery assays and 3D neuronal organoid models for neurodegenerative and neurodevelopmental disorders. He talks about modeling sporadic ALS in a dish, partnering with the Michael J. Fox Foundation, and promoting open science.

Featured Products and Resources:

The Stem Cell Science Round Up

SARS-CoV-2 in the Placenta – Researchers developed induced trophoblast stem cell models to study placental models of infection.

Hematopoietic Stem and Progenitor Cells in the Embryo – Loss of microRNA-128 in zebrafish leads to an expansion of hematopoietic stem and progenitor cells in the aorta–gonad–mesonephros.

Cochlear Organoids – Derived hair cells exhibit cochlear-like structural and functional properties.

Cell Replacement in a Chimeric Mouse Brain – Old or diseased human glial cells in the chimeric mouse brain are eliminated by transplanted young cells.

Photo Reference: Courtesy of Dr. Thomas Durcan

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