Guest:

Dr. Jeffrey Millman is an Assistant Professor of Medicine and Biomedical Engineering at the Washington University in St. Louis. His research focuses on the in vitro production and study of pancreatic insulin-producing β cells from human pluripotent stem cells for use in cellular replacement therapy and drug screening. He joins us to discuss his research.

Resources and Links

Efficient Scarless Genome Editing in Human Pluripotent Stem Cells – Researchers have established a new method for generating ‘scarless’ genetic changes in human pluripotent stem cells that do not
leave selection markers.

Platelets Grown from Stem Cells May be Alternative to Donated Platelets – Platelets generated from adipose-derived stromal stem cells could provide an alternative to donated platelets, which are in short supply and can cause infection in the recipient.

Tackling Treatment-Resistant Cancer – Researchers have found an epigenetic mechanism that cancer cells use to overcome drug treatment.

Honey Bee Protein Keeps Stem Cells Young – A mammalian analog of the active component of honeybee royal jelly acts as a fountain of youth for mouse embryonic stem cells by maintaining their pluripotency.

A Renewable Source of Beige Fat to Overcome Obesity – Reprogramming iPSCs to brown and beige adipose tissue, which burns glucose and improve metabolic function, could provide a new therapeutic strategy to address the health risks of obesity.

Photo Reference: Courtesy of Dr. Jeffrey Millman