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Ep. 244: “The Mammalian Lung” Featuring Dr. Emma Rawlins

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Guest:

Dr. Emma Rawlins is a Senior Group Leader at the Gurdon Institute in the Department of Physiology, Development, and Neuroscience at the University of Cambridge. She talks about modeling fetal lung development using organoids, using single-cell RNA sequencing to create a human lung fetal atlas, and her advice to trainees to follow their hearts.

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The Stem Cell Science Round Up

In Vivo Reprogramming of Astrocytes into Neurons – Researchers refute that Ptbpt1 deletion induces astrocyte-to-neuron conversion.

A Parkinson’s Drug for ALS  – Clinical trial results show that the Parkinson’s disease drug ropinirole delays ALS progression.

Establishment of the Adult Blood System – Researchers identified miR-223 as a negative regulator of murine hemogenic endothelial cell specification and myelopoiesis.

Modeling Preneoplasia in Gastric Organoids – Gastric organoids with inactivated TP53, a common early event in gastric cancer, were created to model the earliest events in human tumor initiation.

Photo Reference: Courtesy of Emma Rawlins.

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