Dr. Madeline Lancaster is a Group Leader at the MRC Laboratory of Molecular Biology in Cambridge, UK. The Lancaster lab has developed cerebral organoids as a model system to better understand human brain evolution, development, and neurodevelopmental disorders. She joined us to discuss her research presentated at the ISSCR 2020 conference.
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Dr. Karl Koehler is an Assistant Professor of Otolaryngology at Harvard Medical School. His lab focuses on using human organoid systems as a platform to model congenital diseases and develop regenerative medicine therapies for the inner ear and various craniofacial tissues.
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Dr. Hans Clevers from the Hubrecht Institute for Developmental Biology and Stem Cell Research is a pioneer in the field, studying the molecular mechanisms of tissue development and cancer of various organs using organoids made from adult Lgr5 stem cells.
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Dr. Josef Penninger is from the University of British Columbia and the Institute for Molecular Biotechnology of the Austrian Academy of Sciences in Vienna, Austria. He was previously on the podcast to talk about his research developing human blood vessel organoids. Dr. Penninger’s team has identified a trial drug that can significantly block early stages of COVID-19 in human blood vessel and kidney organoids.
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Dr. Jeanne Loring is a Professor Emeritus and Director of the Center for Regenerative Medicine at the Scripps Research Institute, and the co-founder of Aspen Neuroscience. Her lab works on a diverse range of projects using iPSCs, including developing cell replacement therapies for Parkinson’s disease, sending neural organoids into space, and partnering with the San Diego zoo to make iPSCs from engangered species.
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