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Dr. Matthias Lutolf is a Professor and Principal Investigator of the Laboratory of Stem Cell Bioengineering at the École Polytechnique Fédérale de Lausanne. His lab uses cutting-edge bioengineering strategies for guiding stem-cell-based development for the assembly of next-generation organoids with improved reproducibility and physiological relevance.
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In this special episode of the Stem Cell Podcast, we speak with three PhD students — Nathasia Mudiwa Muwanigwa, Sarthak Sinha, and Naveed Tavakol — about their research into brain organoids, organ-on-chip systems, and regeneration in different mammals.
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Dr. Miki Ebisuya is a Group Leader at the European Molecular Biology Laboratory in Barcelona. Her lab reconstitutes developmental mechanisms by making artificial gene circuits, and studies interspecies differences by comparing organoids of different animals.
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Dr. Henner Farin is a Young Investigator in the German Cancer Consortium, and a Junior Research Group Leader at the Georg-Speyer-Haus Institute for Tumor Biology and Experimental Therapy. His group uses organoids to study cell signaling in intestinal stem cells and colorectal cancer.
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Dr. Sergiu Pașca is an Assistant Professor of Psychiatry and Behavioral Sciences at Stanford University, and the Bonnie Uytengsu and Family Director of the Stanford Brain Organogenesis Program. His team has developed methods for generating human brain organoids, and uses them to study the programs underlying brain development, assembly and dysfunction.