Dr. Nathaniel Huebsch is an Assistant Professor of Biomedical Engineering at Washington University in St. Louis. His lab focuses on understanding how mechanical cues originating at cell-cell and cell-extracellular matrix contacts influence signaling and fate. They are especially interested in how those cues affect heart development and disease. He talks about cardiac models and cardiomyocyte maturity.
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The Stem Cell Science Round Up
Modeling Early Development – Peri-gastruloids model human post-implantation development into early organogenesis.
Fatty Acid Synthesis in Endoderm Differentiation – Researchers identified a fatty acid synthesis/oxidation shift during early differentiation.
Editing HSCs In Vivo – Scientists designed a strategy to reprogram bone marrow stem cells directly within the body without the need for donor cells or the use of potentially toxic conditioning regimens.
T Cell Therapy for Solid Tumors – Gavo-cel is an engineered T cell therapy tested in patients with mesothelin-expressing solid tumors.