Dr. James Hudson is Group Leader of the Organoid Research Laboratory at the QIMR Berghofer Medical Research Institute in Brisbane, Australia, whose research is focused on developing state-of-the-art bioengineering approaches for human 3D organoids to use for studying cardiac biology and discovering new heart disease therapeutics.

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Stimulating Hair Growth – Investigators have demonstrated that quiescent hair follicles can be stimulated to grow by small molecules that activate autophagy.

Organoid Model of Fibrotic Lung Disease – Researchers used ESC-derived 3D organoids to model fibrotic lung disease, and identified a possible pathogenic mechanism.

Antibody Conditioning for HSC Transplants – A transplant of mismatched HSCs without immune suppression by chemotherapy or radiation was successful in mice by performing a conditioning treatment with six antibodies.

Improving Pancreatic Islet Transplantation – Researchers have identified a protein that improves revascularization of pancreatic islet grafts, and is a potential target for enhancing transplant outcomes in type 1 diabetes.

Reprogramming Scar Tissue into Heart Muscle – For the first time, scientists have developed a stable, reproducible, and minimilistic platform to reprogram human fibroblast cells into cardiomyocytes.

Photo Reference: Courtesy of Dr. James Hudson