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CardiacDisease modelingESCs and iPSCs

Ep. 206: “Heart on a Chip” Featuring Dr. Christine Mummery

By November 16, 2021April 25th, 2023No Comments


Dr. Christine Mummery is a Professor of Developmental Biology at the Leiden University Medical Center and the former President of the International Society for Stem Cell Research. She pioneered studies on cardiomyocytes from human embryonic stem cells and was among the first to inject them in mouse hearts after myocardial infarction. She talks about her recent research developing multi-lineage cardiac model systems like microtissues and organ-chips.

Featured Products and Resources:

The Stem Cell Science Round Up

High-Resolution Whole Organ Imaging – Researchers used synchrotron X-ray tomography to image whole human organs at the cellular level, including lungs infected with SARS-CoV-2.

Fasting and Cancer Stem Cell Escape – In cancer cells, a fasting-mimicking diet activates starvation escape mechanisms that can be targeted.

Tracking HSPC Clones in Zebrafish – Scientists color coded blood stem cells in zebrafish to see which clones became dominant.

A Braking Mechanism for Cardiac Fibroblast Activation – Hif-1α prevents excessive cardiac fibroblast proliferation following myocardial infarction by regulating reactive oxygen species.

Photo Reference: Courtesy of Dr. Christine Mummery

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