Dr. Jackie Damen is a currently a Principal Scientist in Scientific Support for Hematology at STEMCELL Technologies, and was previously the Director of Contract Assay Services. She talks about the company’s culture and growth, and how in her role, she teaches scientists and helps them conduct their experiments. She also discusses systems for drug screening and discovery, opportunities in industry, and her affinity for microscopy and photography.
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Dr. Kelly McNagny is a Professor of Medical Genetics and Biomedical Engineering at the University of British Columbia. His research program is focused on hematopoietic stem cell biology, specifically in understanding the signaling networks that regulate stem cell differentiation and how these cells interact with their microenvironment. He talks about how hematopoietic stem cell differentiation is related to chronic inflammatory disorders, targeting glycosylation in solid tumors, and his international career path.
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Dr. Alejo Rodriguez-Fraticelli is a Group Leader at the Institute for Research in Biomedicine in Barcelona, where his team studies stem cell memory and epigenetics in hematopoiesis, immunity, and leukemia. He talks about setting up a new lab as a “playground for scientists,” how cancer is the “evil twin” of regeneration, and advanced methods for lineage tracing.
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Dr. Jennifer Trowbridge is an Associate Professor at the Jackson Laboratory and an Adjunct Professor at Tufts University. Her lab studies genetics and epigenetics in hematopoietic stem cell biology and leukemia. Their long-term goal is to identify new intervention strategies to extend the “healthspan” of HSCs by maintaining their robust regeneration capacity into older age and reducing risk of development of blood cancers.
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In this special episode of the Stem Cell Podcast, we speak with three PhD students — Nathasia Mudiwa Muwanigwa, Sarthak Sinha, and Naveed Tavakol — about their research into brain organoids, organ-on-chip systems, and regeneration in different mammals.
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