Ep. 231: “Manipulating Stem Cell Fate” Featuring Dr. Shuibing Chen
Dr. Shuibing Chen is the Kilts Family Professor of Surgery at Weill Cornell Medicine. Her lab uses hiPSCs and ESCs for disease modeling and drug screening, with a focus on diabetes and infectious diseases such as Zika and SARS-CoV-2. She talks about her recent genome-wide association study in a dish, the role of philanthropic funding in stem cell research, and the role of industry partnerships in translational research.
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The Stem Cell Science Round Up
Rethinking Hippo Signaling – Scientists found that Hippo signaling is not needed for normal organ growth.
Muscle Stem Cell Regeneration – Researchers identified a subset of dysfunctional aged muscle stem cells with elevated levels of CD47.
Inner Ear Organoids – Scientists used organoids to investigate how CHD7 mutations affect inner ear development.
Islet Transplants Without Immunosuppression – Simultaneous hematopoietic cell and islet transplantation corrects diabetes in mice.
Photo Reference: Courtesy of Dr. Shuibing Chen